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药剂学大纲(Outline of Pharmaceutics)PharmaceuticsI. IntroductionBasic requirements 1. commonly used terms, dosage forms, preparations and pharmaceuticsThe importance and classification of 2. dosage forms (1) the importance of dosage forms(2) classification methods and characteristics of dosage forms3. research contents of pharmaceutics and pharmaceuticsTwo, powderGranules(1) properties and applications of powder powders (1) particle size, particle size distribution and determination methods(2) the specific surface area, porosity, density, fluidity and absorption of the powderWettability and wettability(3) application of powder in Pharmaceutics(two) characteristics and classification of powder 1. powder (1)(2) classificationPreparation of 2. powder (1) material pretreatment(2) the purpose, significance and method of grinding, screening and mixingQuality inspection of 3. powder and hygroscopicity of powder and examples (1) quality inspection items and limit requirements(2) hygroscopicity and preventive measures of powder(3) prescription analysis, preparation process and operation points of powder(three) characteristics and classification of granule 1. granules (1)(2) classificationPreparation and preparation technology of 2. granulesQuality inspection items and limit requirements for quality inspection of 3. granulesThree, tablets (1) basically require the characteristics, types and quality of tabletsQuantity requirement (1) characteristics(2) species(3) quality requirements(two) common excipients, fillers, adhesives and wetting agents, disintegrating agents and lubricants (1)(2) commonly used varieties, abbreviations, properties, characteristics and Applications(three) preparation process of tablets 1. wet granulation (1) granulation purposes(2) wet granulation process(3) drying of wet particles(4) whole granule, total mixing and tabletting (tablet weight calculation)2. dry press (1) crystallization direct compression and dry granulation method and applicable object(2) the characteristics of powder direct compression and the requirements for excipientsMolding and influencing factors of 3. tablet (1) the forming process of tablet(2) the main factors affecting tablet formationThe possible problems in the preparation of 4. tablets and the solutions to the problems such as fragmentation, loose film, sticking and punching, chip weight difference overrun, disintegration delay, dissolution exceeding limit and unqualified uniformity of content and the solutions are discussed(four) the purpose and type of coating 1. coating (1) purpose(2) speciesCoating methods and characteristics of 2. coating methods3. coating materials and procedures (1) varieties, abbreviations, properties, characteristics and applications of commonly used coating materials(2) process flow and operation points(five) quality inspection and prescription design of tablets; quality inspection items and limit requirements of 1. tabletsPrescription design of 2. tablet, prescription analysis of tablet, preparation process and operation pointsFour, capsuleCharacteristics and classification of capsules and pills (1) capsule 1. (1) characteristics(2) classification2. preparation of hard capsule (1) main capsule material and additive of empty capsule(2) specifications of empty capsules(3) handling and filling of materialsPreparation of 3. soft capsules (1) influence factors of soft capsule molding(2) the preparation method of soft capsulePreparation of enteric capsules of 4. enteric coated capsules5. quality inspection and examples (1) quality inspection items and limit requirements(2) formulation analysis, preparation process and operation points of capsule(two) pill 1. drop pill agent (1) characteristics(2) common matrix and condensation agent(3) preparation process2. small pill (1) characteristics(2) preparation methodsFive. Suppository (1) basically require the classification, characteristics and quality requirements of suppositories (1)(2) characteristics(3) quality requirements(two) the function and requirement of matrix 1. matrix of suppository (1) the role of matrix(2) the requirement of ideal matrix2. commonly used matrices and additives (1) classification of matrices(2) the properties, characteristics and applications of common matrices(3) the role of commonly used additives(three) the function of suppository and the factors affecting the absorption of drugs in suppository 1. the effect of suppository (1) local action(2) whole body actionTwoFactors affecting the absorption of drugs in suppository (1) physiological factors(2) physical and chemical properties of drugs(3) matrix and additive(four) preparation and quality evaluation of suppository 1. preparati
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