MedqicalGenetics04基因突变的分孙细胞生物学改应cellulareHectsofgenezutationMedqicalGenetics1.GenescanbemutatedinmanywaysThemostcommongenechangeinvolvesasinglebasemismatch-amisspelling-placingthewrongbaseintheDNA.Atothertimes,asinglebasemaybedroppedoradded.AndsometimeslargepiecesofDNAaremistakenlyrepeatedordeleted.MedqicalGeneticsRepetitonMedqicalGeneticsWhenagenecontainsamutation,theproteinencodedbythatgeneislikelytobeabnormal.MedqicalGeneticsDNA-RNA-ProteinEEBnmembraneMedqicalGeneticsAlteredDNA-AlteredProteinEmembraneRibosomeMWedqicalGenetics2.SomaticversusgermlinemutationsGenemutationscanbeeitherinheritedfromaparentoracquired.MedqicalGenetics觐Normal!ProgenyMutantPIOgenyN根=MedqicalGeneticsHereditarymutationsarecarriedintheDNAofthereproductivecells.Whenreproductivecellscontainingmutationscombinetoproduceoffspring,themutationwillbeinalloftheoffspringsbodycells.MedqicalGeneticsThefactthateverycellcontainsthegenechangemakesitpossibletousecheekcellsorabloodsampleforgenetesting.