The Bleeding Disorders Feature of the bleeding disorders Spontaneous hemorrhage Or severe bleeding in response to relativelyminor stimuli Abnormalities of hemostatic function Hemostatic mechanisms Vascular function in hemostasis Platelet function in hemostasis Blood coagulation and fibrinolysis Anti-coagulation function Vascular function in hemostasis The vessel wall Endothelium:the regulationof hemostasis Platelet function in hemostasis PlateletUltrastructure ofplatelet Platelet functionPlatelat adhesionreactionPlatelet aggregationreactionPlatelet releasereaction