2013 6 10 6 Chin JM ed Ultr asound Electr onicEdition J une 2013 Vol 10 No 6 489 马姣姣 丁红 徐本华 毛枫 朱宇 莉 徐晨 王文平 DO I 10 3877/ cma j issn 1672- 6448 2013 06 014 200802- 10 B112 200032 、 、 、 、 、 Email ding hong z s-hospital sh cn 【 】 。 178 、 、 、 5 、 、 6 1 、 0 。 、 RO C 。 、 、 Z=10 188、 9 843、 10 705 P 0 001 。 、 RO C 0 936、 0 919、 0 964。 5 3 79 6% 91 2% 6 2 91 8 % 81 2% 11 5 93 6% 92 3%。 5 。 【 】 Clin ic a l v a lu e a n d o p t im a l d ia g n o s t ic p o in t o f u lt r a s o u n d in t h e d ia g n o s is o f t h y r o id le s io n s M A Ji ao -ji ao DI N G H o n g XU Be n -h u a M A O F e n g ZH U Yu -l i XU Ch e n W A N G W e n -p i n g De p ar t m e n t o f Ul t r as o u n d Zh o n g s h an H o s p i t al F u d an Un i v e r s i t y Sh an g h ai 200032 Ch i n a Co r r e s p o n d i n g au t h o r DI N G H o n g Em ai l d i n g h o n g z s -h o s p i t al s h cn 【 Ab s t r a c t】 Ob j e c t iv e To discuss the combined v alue ofgr ay -scale ultr asound G SUS and contr ast-enhanced ultr asound CEUS inthe diagnosisofbenignandmalignant thy r oidlesionsandto ex plor e the optimaldiagnosticpoint ofscor ingmethod M e t h o d s Ultr asoundimagesof178 thy r oidlesionsconf ir med by pathology w er e sy nthetically r ev iew ed by scor ing5 G SUSindicator s includingshape or ientation inter ior echogenicity halo sign micr ocalcif ication and6 CEUSindicator s includingr elativ e ar r iv altime ofmicr obubbles in the per ipher y and inter ior peak per ipher y and inter iorechogenicity per ipher al r ing-enhancement and homogeneity ofenhancement O ne positiv e indicatorscor ed one point The optimaldiagnostic points and theirclinical v alue w er e ex plor ed accor ding to RO C cur v es R e s u lt s Scor es ofG SUS CEUS and the combination ofG SUSand CEUSw er e signif icantly dif f er ent Z =10 188 9 843 10 705 allP 0 001 Ar eas underRO C cur v es ofG SUS CEUSand the combination ofG SUSand CEUSw er e 0 936 0 919 and 0 964 r espectiv ely Thr ee ormor e positiv e G SUS indicator s off iv e in a thy r oid lesion pr edicted that the thy r oid lesion w as malignant w ith the sensitiv ity of79 6% and the specif icity of91 2% Tw o ormor e positiv e CEUSindicator s ofsix in a thy r oid lesion pr edicted that the thy r oid lesion w as malignant w iththe sensitiv ity of91 8 % and the specif icity of81 2% Fiv e ormor e positiv e G SUS and CEUS indicator s of elev en in athy r oid lesion pr edicted that the thy r oid lesion w as malignant w iththe sensitiv ity of93 6% and the specif icity of92 3% The ar eas underthe RO C cur v e ofG SUSand CEUSw er e 0 936 and0 919 The ar ea underthe RO C cur v e ofthe combination ofG SUSand CEUSw as0 964 lar gerthan the ar eas underthe G SUSRO C cur v e andthe CEUSRO C cur v e Co n c lu s io n Ultr asoundisv aluable inthe dif f er entialdiagnosis 490 2013 6 10 6 Chin JM ed Ultr asound Electr onicEdition J une 2013 Vol 10 No 6 ofbenign and malignant thy r oid lesions and the combination ofG SUSand CEUSis the most v aluable w ith 5 points as the optimaldiagnosticscor ingmethod 【 Ke y w o r d s】 Ultr asonogr aphy Contr ast media Thy r oid nodule Diagnosis dif f er ential 、 、