广泛的 in an extensive survey进行 conduct， perform, carry out, 降，少，缺 decrease, reduction, reduced, diminish, loss, suppression, deficient, low, weak, faint, light, absence, absent, undetectable, lack ,defective, negative, poor, impaired, greatly reduced or completely absent, frequently lost or down-expressed, presented discontinuous and weaker expression, completely negative, was not detectable or dramatically reduced, very faint, was undetectable or barely detectable, no expression was found, 差别 gaps between, differentiate between, discrepancies，no intergroup differenceNo statistically significant differences in survival were found for MMC or MPMA.Although MMC and MPMA decreased with increasing nuclear grade and TNM stage, this difference failed to achieve statistical significance.存在，出现 occurred, occurrence ,existed, existence, presence, present多数，少数 the overwhelming majority of, in the majority of cases ，a marked majority, handful方法 approaches, avenues, methods, techniques, means, tools发生率 Incidence, frequency, prevalenceIn contrast with regions of high incidence, the mutation spectrum did not show a high prevalence of mutations at A:T base pairs.发现，阐明，报道，证实 verify, confirm, elucidate, identify, define, characterize, clarify, establish, ascertain, explain, observe, illuminate, illustrate，demonstrate, show, indicate, exhibit, presented, reveal, display, manifest，suggest, propose, estimate, prove, imply, disclose，report, describe，facilitate the identification of ，screening ，isolation改变 change, alteration, 高，增加 high, enhanced, elevated, increased, forced各种，多种 in multiple types of neoplasia, in various types of apoptosis, in a variety of tumors关系，相关，参与 closely involved in, associated,角色，起作用 role, part （limited, potential, early, possible role），serve antiapoptotic functions可能性 feasibility密切地 intimately难理解的，似谜的 enigmatic (x remains enigmatic)潜在假定的 potential, candidate, putative,缩写 abbreviations识别，辨别 discernment 事件Metastasis to the liver is a common event in clinical oncology.a putative tumor initiating eventa (more, extremely, highly, rather, fairly) common initial, a common event in the signal transduction mechanisms of, in the signal transduction processesa common event associated with the mechanisms ofa common early event in responses of, after high-dose chemotherapya common event following gestational exposure to immunotoxicantsa common event （that occurs） during apoptosis isa common event during oncogenic transformation, in neoplastic transformation that directly or indirectly involves activation of specific tyrosine kinase signaling pathwaysa common event through whicha common event in vivoa rather common event of unknown biological significancea common event resulting from heterogeneous aberrationsa common event regardless of histological subtyping, but does not bear any pejorative significancea common event contributing toa rare, common, prerequisite, central, major, transient, initiation, stressful, critical, crucial, secondary, independent, regulatory, early, earlier, late, later, subsequent, circumstantial, untoward, upstream, irreversible, very frequent event提供，帮助 provide, supply, help (to), contribute to, offer, allow, dedicate, devote, assist in调节（失调，上调，下调）dis-regulation, dys-regulation, up-regulation, up-expression, over-expression, down-expression, down-regulation, 推测 presume,speculate ,confer, conjecture ,guess, deduce，deduction (推论)无所不在地(表达，如 MEN1)ubiquitously显著,优先的 prominent, pronounced, obvious, marked, predominant, strong, striking ,notable, Conspicuously, remarkably，significant, preferential, prevalence, prevalent,相关性related, more relevant with ，the relevance ofno intergroup difference，irrespective ofThere was no significant correlation to gender, age, clinical symptoms, histology, T or N status, TNM stage, or tumor location.Neither eNOS nor nNOS expression was associated with vascular density, tumor grade or the TNM status of the tumors.No correlations were found between bFGF and age, menopausal status, TNM or pTNM, histology, SBR grading or steroid receptors.we did not find any correlation between bax expression and any clinicopathologic parameters (sex, age, TNM status, tumor grade, histological type).相同，同等并列The coordinated induction of all three FOXO3a targets prompted us to examine the status of FOXO3a itselfwith a similar pattern to协同，加强synergize with研究 analysis, survey, study, research, investigation, experiments, trial, observations, assessment, inquiry, examinations ,pursue investigation into, analyze, detect, determinate, be focused on, measure, examine, test, assess, evaluate, explore,一致which is in accord with the resultswhich corroborated the resultswhich supported the results优缺点 merits and drawbacks，beneficial and detrimental异常 aberration, abnormality重要 crucial, key, important, major, be of critical importance 相反On the contrary, In contrary,but quite on the contraryin sharp contrast,contrary to what would be expectedContrary to the expectation thatContrary to previous beliefs,Con