1, 鷿, 2010628,2,3,4, ,: 溦,5,2050 (p) pp p. 2060 . 2070 p p.,6,p,. Y R XP,O,O,R,7,綾 LD5010J/K p . LD5010100J/Kp p LD501001000J/Kp . LD5010005000J/K.,8,1. 2. 3.,9,: : :,10,11,12,13,14,Ach,M2,M1M4,15,16,;𵨼p,. .,17, ,18,(M),; ppp; ppp; ; (); pp;,19,(N),񾭼 ,; ; ; ; 󽻸: pp,20,pp; pp; 鴤p;,21, : : 񾭽 񾭼 鴤,22,23, 񾭲p 23 鼡(NTE) p 2496 𺦣 ,24,. pp; ; ,25,1. 2. 3. 4. ,26,顿,:CHE : pp ,27, ,28, :p,29, 38.5 ChE ,30, ChE ,31, ChE ,32, ChE ,33, M,CHE7050%. M,N ,CHE5030%. MpN,p 鴤pp ,CHE30%.,34,. p p,35,36,37,38,., ppp pp ,39, ( ) ChE ChE,40,ChE,41,ChE,1. 2. 3. 4. 5. ,42, 0.250.5g, 0.50.75g, 0.751g,IV, 1/2h ,2 0.5g, 21,3 0.25g,IV, . 0.4g, 0.81.2g, 1.21.6g,IV, IV IV 2h 0.4g, 0.4g,IV, 1 2h. 6h ,43, ChE5060% , ,ChE, ,44, :ppp :,.񾭺,.,45,:103012,. :pppp(100120/). ,.,46,:p(140/) ppppp鴤. ,47, 12mg 12 25mg 1520 510mg 1015 ,48,(M) (N) , 1J,2,0.56,10.34,2494.17%.,49, 񾭩pp (M2) p.,50,51, MMM1M3,M2M4.M2 M4 ,52,1. ,2.,3.,53, (mg/) * 12 01000 24 10001500 46 15002500 *1g1.5g,54,1. 򡰰 (1) (2) (3) 泱 2. 3. ,55,., pp ppp , p,𲽼,37.,56,p ,57, ,58,񾭲,2496,. :,񾭣. : ,59,1? 2 500ml 3 ? ,60,4 ? 5? 񣬿 6IMS? N塰񾭼 ,61,7񾭲? 8 MACH ,62,