Reproductive system第一页，共四十页。lMale reproductive system.lFemale reproductive system.第二页，共四十页。ltestislGenital excurrent ductslAccessory sex glandslpenis第三页，共四十页。bladderDuctus deferensepididymistestisTunica vaginalis Corpus cavernosum Corpus spongiosumSeminiferous tubuleStraight tubuleRete testisEfferent ductuleDuctus epididymisSeminal vesicleprostateBulbourethral gland第四页，共四十页。summarysummaryl l tunica albugineatunica albugineaseptumseptuml l lobules of testis lobules of testis l l in each lobule, consist of in each lobule, consist of seminiferous tubules.seminiferous tubules.ll CT stromaCT stroma , contains interstitial , contains interstitial cells .cells .一、一、testis第五页，共四十页。Testis& epididymis第六页，共四十页。（一）（一）（一）（一）seminiferous tubuleseminiferous tubule seminiferous epitheliumlSupporting cells/ sertoli cellslSpermatogenic cells第七页，共四十页。Seminiferous tubule第八页，共四十页。spermatogoniumBasal laminaPrimaryspermatocyteSertoli Cspermatid第九页，共四十页。1.1.Spermatogenic cellsSpermatogenic cells spermatogoniumspermatogonium primary spermatocyteprimary spermatocyte secondary spermatocytesecondary spermatocyte spermatidspermatid spermatozoaspermatozoaspermatogenesis第十页，共四十页。lllocation: closely attach to basal location: closely attach to basal lamina of spermatogenic Epi.lamina of spermatogenic Epi.l l round round，organells poorly-organells poorly-developeddevelopedll differentiate into differentiate into primary primary spermatocytespermatocyte（1）spermatogonium第十一页，共四十页。A型型B型型第十二页，共四十页。spermatogonia第十三页，共四十页。（2 2）primary spermatocyte primary spermatocyte l l attach to the luminal surface of the attach to the luminal surface of the spermatogonia.spermatogonia.ll large. large.l l after 1 st meiotic division after 1 st meiotic division，produce 2 secondary spermatocyteproduce 2 secondary spermatocyte。第十四页，共四十页。Primary spermatocytes第十五页，共四十页。（3 3）secondary spermatocytesecondary spermatocytel lNot easy to be seen in section.Not easy to be seen in section.l lAfter the second meiotic After the second meiotic divisiondivision，form 2 spermatids.form 2 spermatids.第十六页，共四十页。 （4）spermatidladjoining to the lumen.lNo division，undergo extensive cell remodeling , as they differentiate into sperm.lthis process is called spermiogenesis。第十七页，共四十页。（5）spermlShaped pollywog，divide into head sperm & tail sperm。lhead: nucleus+acrosome。lIn acrosome, variant acrosomal enzymes. ltail: motile equipment .第十八页，共四十页。sperm第十九页，共四十页。sperm第二十页，共四十页。 2. supporting ClSertoli C.l stained lightly，nucleulus is obvious。l sides with tightly junction.l support , nutrient spermatogenic cells.第二十一页，共四十页。Supporting C第二十二页，共四十页。Blood-seminiferous tubule barrierBlood-seminiferous tubule barrier：llThe structure , prevent large molecular The structure , prevent large molecular The structure , prevent large molecular substances exchange between the blood and substances exchange between the blood and substances exchange between the blood and the seminiferous tubule.the seminiferous tubule.the seminiferous tubule.l llcostituentscostituentscostituents：endothelium & basal lamina of cap. endothelium & basal lamina of cap. endothelium & basal lamina of cap. 、CTCTCT、basal lamina of spermatogenic epi. And the basal lamina of spermatogenic epi. And the basal lamina of spermatogenic epi. And the tight junctions of adjoining supporting C .tight junctions of adjoining supporting C .tight junctions of adjoining supporting C .llTight - junction Tight - junction is the essential constituent of is the essential constituent of is the essential constituent of blood-seminiferous tubule barrier.blood-seminiferous tubule barrier.blood-seminiferous tubule barrier.第二十三页，共四十页。（二）（二）interstitial ClLeydig C, In group, large , polygonal, highly eosinophilic .lSteroid-secreting C: elaborate sER, Mit. With cristae. Secret testosterone/androgen第二十四页，共四十页。Interstitial C第二十五页，共四十页。l maintain spermatogenesis & secondary sex characteristics.lBe responsible for the development of genital organs in male.lKeep sex capability.Functions of leydig C第二十六页，共四十页。（三）（三）（三）（三）straight tubule & rete testisstraight tubule & rete testisllStraight tubuleStraight tubuleStraight tubule: near the mediastinum of the : near the mediastinum of the : near the mediastinum of the testis ,where seminiferous tubule assume a testis ,where seminiferous tubule assume a testis ,where seminiferous tubule assume a short straight course. short straight course. short straight course. llRete testisRete testis: the straight tubule empty into the : the straight tubule empty into the : the straight tubule empty into the rete testis, an anastomosing channel system rete testis, an anastomosing channel system rete testis, an anastomosing channel system within the mediastinum.within the mediastinum.within the mediastinum.llSpermSpermSperm produced in seminiferous tubule pass by produced in seminiferous tubule pass by produced in seminiferous tubule pass by straight tubule & rete testis , leaving testis and straight tubule & rete testis , leaving testis and