中国药科大学药物化学期末试卷2013-2014 学年第二学期专业班级学号姓名 题号得分核分人：一、写出下列药物的名称及主要临床用途（每小题 2 分，共 20 分）（忘了）二、写出下列药物的结构式及主要临床用途（每小题 2 分，共 20 分） 阿昔洛韦氯丙嗪苯巴比妥喷他佐辛头孢氨苄苯海索环磷酰胺克霉唑甲苯磺丁脲硝酸甘油三、写出具有下列词尾或词头的药物的作用靶位及主要临床用途（每小题 2分，共 10 分）作用靶位主要临床用途-mustine-oxacin-vudine-pril-oxicam四、问答题1. 先导化合物有哪些发现途径？各举一例说明。2. 烷化剂分为哪几类？举例说明。3. 试说明糖皮质激素的结构改造方法？4. 四环素不稳定性的原因？为何不能与牛奶同时服用？5. 试说明 NSAIDs 的作用机制？五、合成题1. 以 2,6-二氯苯酚为原料合成双氯芬酸钠2. 以 2-甲基丙二酸二乙酯为原料合成吉非贝齐3. 以硫代乙酸和 2-甲基丙烯酸为原料合成卡托普利“”“”At the end, Xiao Bian gives you a passage. Minand once said, people who learn to learn are very happy people. In every wonderful life, learning is an eternal theme. As a professional clerical and teaching position, I understand the importance of continuous learning, life is diligent, nothing can be gained, only continuous learning can achieve better self. Only by constantly learning and mastering the latest relevant knowledge, can employees from all walks of life keep up with the pace of enterprise development and innovate to meet the needs of the market. This document is also edited by my studio professionals, there may be errors in the document, if there are errors, please correct, thank you!