1 / 7 四川大学期末考试试卷(A，本卷共 3 页) （20052006学年第一学期）课程号： 50124530 课序号：课程名称：病理生理学任课教师：杨志梅，黄英, 李绚，适用专业年级： 03 级临床医学、口腔医学七年制学生人数：（ 83+89+60 =232）印题份数： 250 姓名：班级：学号：成绩：考试须知四川大学学生参加由学校组织或由学校承办的各级各类考试，必须严格执行四川大学考试工作管理办法和四川大学考场规则。有考试违纪作弊行为的，一律按照四川大学学生考试违纪作弊处罚条例进行处理。四川大学各级各类考试的监考人员，必须严格执行四川大学考试工作管理办法、四川大学考场规则和四川大学监考人员职责。有违反学校有关规定的，严格按照四川大学教案事故认定及处理办法进行处理。I. Term explanation (3 points/each 8) 1. Pathological process 5. Paroxysmal nocturnal dyspnea 2. AG 6. Respiratory Failure 3. Stress ulcer 7. False neurotransmitters 4. Fever 8. Acute renal failure II Fill in the blanks (1 point/each blank 16) 1. Hypertonic dehydration：H2O loss ( ) Na+ loss, plasma Na+( ), plasma osmotic pressure ( ). 2. Basic pathogenesis of edema includes ( ) and ( ). 3. Stress is defined as ( ) and 精选学习资料 - - - - - - - - - 名师归纳总结 - - - - - - -第 1 页，共 7 页2 / 7 ( ) response to variety of stimuli, mainly with the activation of sympathetic-adrenal medulla and hypothalamus-pituitary- adrenocortical axis. 4. In circulatory hypoxia,CaO2-CvO2 is ( ). 5. Disturbances of myocardial energy metabolism in heart failure means ( ) and ( ). 6. The initiation of shock include ( ), ( ) and （）7. Mechanisms of blood NH3 include ( ) and ( ). 8. The primary pathogenesis of renal anemia is ( ). 本题 3 页，本页为第 1 页精选学习资料 - - - - - - - - - 名师归纳总结 - - - - - - -第 2 页，共 7 页3 / 7 . Choose questions (choose a best answer from the four candidates, 1 point /each 20 fill the answer in the table) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 1. Incorrect description about the brain death is ( ) A. irreversible coma C. breath stop B. dilated and fixed pupil D. heart arrest 2.During severe hyperkalemia the myocardium shows ( ) A. excitability conductivity autorhythmicity B. excitability conductivity autorhythmicity C. excitability conductivity autorhythmicity D. excitability conductivity autorhythmicity 3. Fever especially in defervescence period usually has a trend to occur ( ) A. hypertonic dehydration C. isotonic dehydration B. hypotonic dehydration D. water intoxication 4. Which one of the followings is not the endogenous pyrogens ( ) A. endotoxin C. IL-1 B. TNF D. Interferon 5. The major compensation for chronic respiratory alkalosis is ( ) A. shift of ions across cell membrane and intracellular buffers 精选学习资料 - - - - - - - - - 名师归纳总结 - - - - - - -第 3 页，共 7 页4 / 7 C. renal compensation B. respiratory compensation D. blood buffers 6. Mixed Acid-Base Disorders could not include ( ) A. respiratory alkalosis + metabolic acidosis B. respiratory acidosis + respiratory alkalosis C .metabolic alkalosis + metabolic acidosis D .respiratory alkalosis + metabolic alkalosis 7. The primary mechanism of Bleeding in DIC is ( ) A .Excessive consumption of platelet and clotting factors B .Activation of fibrinolytic system C .FDPs inhibit fibrin polymerization D .FDPs inhibit thrombin 8. The incorrect one for cyanosis is ( ) A .Hypoxia doesn t mean an absolute existence of cyanosisB .HHb 5g% in blood will cause cyanosis C .PaO2 6.7 kPa (50mmHg), O2 saturation of Hb 80% can cause cyanosis D .Hypoxia caused by severe anemia usually has obvious cyanosis 9. ( ) is not the cause of metabolic acidosis A. serious diarrhea C. hypokalemia B. .diabetic ketonemia D. acute renal failure 10. The primary mechanism of DIC is ( ) 精选学习资料 - - - - - - - - - 名师归纳总结 - - - - - - -第 4 页，共 7 页5 / 7 A. Activating factor - initiation of intrinsic clotting pathway B. Excessive destruction of RBC C. Thromboplastic materials entering blood D .Activation of extrinsic clotting pathway 11.DIC occurs relative easily in obstetric accident is due to ( ) A. hypercoagulable state of blood B. inhibition of mononuclear phagocyte system C. injury of endothelium of capillary D .disturbance of placenta circulation 12. High-output heart failure occurs in ( ) A. coronary heart disease C. myocardiopathy B. hypertension heart disease D. arteriovenous fistula 13. Which one is not the effect of hyperkalemia on skeleton muscle ( ) A. muscle weakness C. Hyperpolarized blocking of muscle cells B .muscle paralysis D. the absolute value of rest 本题 3 页，本页为第 2 页精选学习资料 - - - - - - - - - 名师归纳总结 - - - - - - -第 5 页，共 7 页6 / 7 membrane potential of muscle cells 14. The increase of body temperature induced by ( ) is called hyperthermia A. pregnancy C. pneumonia B. congenital deficiency of sweat gland D. physical exercise 15. The characteristics of type respiratory failure are ( ) A. PaO2 60 mmHg C. PaO2 40 mmHg B. PaO2 50 mmHg D. PaO2 60 mmHg 16The change of which following items will be the same in hypotonic and circulatory hypoxia（）A. PaO2 C. Oxygen capacity of artery blood B. Oxygen content of artery blood D. Oxygen saturation of artery blood Hb 17.In hepatic encephalopathy the GABA comes mainly from ( ) A. synthesis in CNS C. synthesis in liver B. intestine D. producing by muscle 18. Which change occurred in early stage of shock has the compensative effect ( ) A. vasoconstriction C. hemotocrit B. blood stagnant D. acidosis 19. The most vulnerable organ to shock is ( ) A. Brain C. lung B. heart D. kidney 20. The essential pathogenic mechanism for stress ulcer is ( ) A. ischemia of gastric mucosa C. disturbance of 精选学习资料 - - - - - - - - - 名师归纳总结 - - - - - - -第 6 页，共 7 页7 / 7 digestive function B. acidosis D. malnutrition. Answer questions (10 points/each) 1.Please describe effects of acidosis on cardiovascular system. 2.Why microcirculatory failure stage is also called difficult (refractory) phase of shock? 3.Please describe the pathogenic mechanisms of pulmonary encephalopathy. 4.Please describe the pathogenic mechanisms of renal hypertension. 精选学习资料 - - - - - - - - - 名师归纳总结 - - - - - - -第 7 页，共 7 页