以优化瘤胃健康来提高以优化瘤胃健康来提高奶牛营养效率奶牛营养效率Enhancing Nutritional Efficiency inDairy Cattle through Improved Rumen Health Ilkyu Yoon, Ph. D. Diamond V美美国国October, 2012以优化瘤胃健康来提高奶牛营养效率中国奶业进展中国奶业进展 ChinaDairyIndustryChinaDairyIndustryDairy populationMilk yieldDr.J.X.Liu,2012Dr.J.X.Liu,2012 刘建新教授刘建新教授 ,2012 奶牛头数奶牛头数奶产量奶产量奶奶牛牛头头数数 ( (百百万万头头) )产产奶奶量量 ( (百百万万公公吨吨) )以优化瘤胃健康来提高奶牛营养效率高质量粗饲料短缺高质量粗饲料短缺ShortofGoodQualityForagesShortofGoodQualityForagesDemDemand 需求需求 650 x 106 MT (6亿亿5千万吨千万吨) Supply 供应供应420 x 106 MT (4亿亿2千万吨千万吨) Deficit 短缺短缺230 x 106 MT (2亿亿3千万吨千万吨)ChiChina Ministry of Agriculture (2002008) 中国农业部中国农业部 (2008)Dr.J.X.Liu,2012Dr.J.X.Liu,2012 刘建新教授刘建新教授 ,2012 10%/Yr10%/10%/年年以优化瘤胃健康来提高奶牛营养效率饲料效率变得越发重要饲料效率变得越发重要FeedEfficiencyBecomesMoreImportantFeedEfficiencyBecomesMoreImportant需求增加需求增加& &竞争竞争IncreasedDemandIncreasedDemand&Competition&Competition提高饲料效率提高饲料效率ImprovedImprovedFeedEfficiencyFeedEfficiency饲料成本增加饲料成本增加IncreasedFeedCostIncreasedFeedCost提高成本效率提高成本效率ImprovedImprovedCostEffectivenessCostEffectiveness饲料资源有限饲料资源有限LimitedLimitedFeedResourcesFeedResources以优化瘤胃健康来提高奶牛营养效率健康的瘤胃健康的瘤胃= =效率最佳化效率最佳化HealthyRumenHealthyRumen=MaximumEfficiencyMaximumEfficiency以优化瘤胃健康来提高奶牛营养效率瘤胃的健康总是受到挑战瘤胃的健康总是受到挑战 RumenHealthIsUnderChallengeRumenHealthIsUnderChallengeRation IngredientVariationFeed SortingLimited Bunk SpaceInaccurateTMR MixingForage QualityRumen EfficiencyStarch FermentabilityHeat StressInconsistent Feed Delivery Time粗饲料品质粗饲料品质淀粉发酵率淀粉发酵率TMRTMR混合不精确混合不精确饲料运送时间饲料运送时间不一致不一致饲槽空间不足饲槽空间不足挑食精料挑食精料热应激热应激日粮原料变异日粮原料变异以优化瘤胃健康来提高奶牛营养效率提高瘤胃功能的独特技术提高瘤胃功能的独特技术： AUniqueTechnologyThatEnhancesAUniqueTechnologyThatEnhancesTheTheRumenRumen FunctionFunction: :达农威益康达农威益康XPXP酵母培养物酵母培养物DiamondVYeastCultureDiamondVYeastCulture以优化瘤胃健康来提高奶牛营养效率wThePROCESS,perfectedandimprovedover69yearstoensureconsistencyandcontinuityinallourproducts过过程程: :超过超过6969年的完美与改善来保障产年的完美与改善来保障产品的一致性与连续性品的一致性与连续性wTheFORMULATIONSthatproducetheuniqueblendofmetabolitesthatcannotbematchedorduplicated配配方方: :生产出无可匹配且无法复制的生产出无可匹配且无法复制的、独特的代谢物组成独特的代谢物组成wTheTECHNOLOGYthatcontinuestoharnessthebenefitsoffermentationinemergingways,todeliverthemostinnovativesolutionsforourcustomers发酵工艺发酵工艺: :持持续利用新兴工艺技术所得到的发酵续利用新兴工艺技术所得到的发酵好处，来为我们的客户提供最具创好处，来为我们的客户提供最具创新性的解决方案新性的解决方案达农威微生物发酵工艺达农威微生物发酵工艺DiamondVMicrobialFermentationDiamondVMicrobialFermentation酵母扩繁系统酵母扩繁系统酵母膏酵母膏液态扩繁培养基原料液态扩繁培养基原料液态发酵液态发酵干燥谷物原料干燥谷物原料发酵培养液发酵培养液干混合压出物干混合压出物挤压处理挤压处理干混合压出物干混合压出物混合混合干混合压出物干混合压出物固态发酵固态发酵发酵后干混合发酵后干混合压出物干燥压出物干燥粉碎粉碎完成的产品完成的产品以优化瘤胃健康来提高奶牛营养效率发酵使结果不同发酵使结果不同 FermentationmakesthedifferenceFermentationmakesthedifferenceFermentationFermentation发酵发酵发酵发酵以优化瘤胃健康来提高奶牛营养效率2000X magnification达农威酵母培养物达农威酵母培养物DiamondVYeastCultureDiamondVYeastCulture http:/www.sigmaaldrich.comProteinLysineCuZnCaPeptidesAEBLeucineNucleicAcidsProteinatesIntracellular ComponentsExtracellular MetabolitesOrganicAcidsOligosaccharidesPeptidesNucleotidesPolyphenolsProtein细胞外代谢产物细胞外代谢产物小肽小肽蛋白质蛋白质核苷核苷寡糖寡糖芳香化合物芳香化合物有机酸有机酸细胞内容物细胞内容物蛋白酶蛋白酶核酸核酸蛋白质蛋白质铜铜钙钙赖氨酸赖氨酸亮氨酸亮氨酸锌锌维生素维生素A A维生素维生素B B维生素维生素E E小肽小肽酵母酵母细胞壁细胞壁以优化瘤胃健康来提高奶牛营养效率达农威益康达农威益康XPXP能优化瘤胃功能性能优化瘤胃功能性微生物的生长与平衡微生物的生长与平衡：DiamondVYeastCultureDiamondVYeastCulturemmaximizeaximizes sthethegrowthofgrowthoffunctionalfunctional r rumenumenmmicrobesandicrobesando optimizeptimizes s t theirheirb balance:alance:维持瘤胃功能的关键者维持瘤胃功能的关键者TheKeyPlayersofRumenFunctionTheKeyPlayersofRumenFunction以优化瘤胃健康来提高奶牛营养效率瘤胃三种主要的微生物瘤胃三种主要的微生物Three Major Rumen Microorganisms以优化瘤胃健康来提高奶牛营养效率Courtesy of Agriculture and Agri-Food Canada正在作用中的瘤胃微生物正在作用中的瘤胃微生物Rumen Microorganisms in Action以优化瘤胃健康来提高奶牛营养效率7.812.319.625.5051015202530Billion CFU/mlKentuckyUtah StateControlDiamond V XPHarrison et al. 1988. J. Dairy Sci. 71:2967-2975.Wiedmeier et al. 1987. J. Dairy Sci. 70:2063-2068.+30%+58%达农威益康达农威益康XP增加瘤胃细菌总数增加瘤胃细菌总数XP Increases Total Rumen Bacteria每每毫毫升升十十亿亿个个菌菌落落形形成成单单位位肯塔基大学肯塔基大学尤他州大尤他州大对照组对照组达农威益康达农威益康以优化瘤胃健康来提高奶牛营养效率66*120*00.020.040.060.080.100.120.140.16Billion CFU/mlKentuckyControlDiamond V XP2.5*4.0*0.01.02.03.04.05.06.0Billion CFU/mlUtah StateControlDiamond V XPHarrison et al. 1988. J. Dairy Sci. 71:2967-2975.Wiedmeier et al. 1987. J. Dairy Sci. 70:2063-2068.+59%*P 0.05+82%*P 0.05达农威益康达农威益康XP增加纤维分解菌的数量增加纤维分解菌的数量XP Increases Fiber-digesting Bacteria肯塔基大学肯塔基大学尤他州大尤他州大对照组对照组对照组对照组达农威益康达农威益康达农威益康达农威益康每每毫毫升升十十亿亿个个菌菌落落形形成成单单位位每每毫毫升升十十亿亿个个菌菌落落形形成成单单位位以优化瘤胃健康来提高奶牛营养效率0.200.230.300.10*0.14*0.17*0.10*0.29*0.43*0.03*0.10*0.30*0.00.10.20.30.40.5HD4H18B159T81OD, 600nmControl1% XP Filtrate5% XP FiltrateCallaway and Martin. 1997. J. Dairy Sci. 80:2035-2044.SelenomonasruminantiumMegasphaeraelsdenii*P 0.0524 Hour Turbidity达农威益康达农威益康XP增加乳酸利用菌的数量增加乳酸利用菌的数量XP Increases Lactate-utilizing Bacteria反刍月形单胞菌反刍月形单胞菌埃及巨球形菌埃及巨球形菌光光学学密密度度24小时培养液混浊度小时培养液混浊度对照组1%益康XP滤液5%益康XP滤液以优化瘤胃健康来提高奶牛营养效率Mao et al. 2012. Submitted.*P 0.05达农威益康达农威益康XP增加瘤胃真菌数量增加瘤胃真菌数量XP Increases Rumen Fungi稻草稻草 玉米秸秆玉米秸秆不带棒玉米青贮不带棒玉米青贮带棒玉米青贮带棒玉米青贮对照组对照组每升每升1 1克益康克益康XPXP以优化瘤胃健康来提高奶牛营养效率GenusControlControl对照组对照组XPXP益康组益康组Entodinium*EpidiniumDiplodiniumEremoplastromEudiplodiniumOstracodiniumDiploplastromMetadiniumEnoploplastromElytroplastromIsotrichaDasytricha*Unidentified87.72.1-0.21.02.20.81.2-1.10.62.70.469.61.8-0.41.24.32.10.80.20.63.215.50.3肉牛瘤胃中原生虫族群分布百分比肉牛瘤胃中原生虫族群分布百分比PercentgenericdistributionofrumenprotozoainsteersPercentgenericdistributionofrumenprotozoainsteersArakakietal.,2000.Anim.FeedSci.&Technol.84:121-127533%574%* P 0.05-21%达农威益康达农威益康XP平衡瘤胃原生虫族群平衡瘤胃原生虫族群 Balances Rumen Protozoal PopulationIncreases microbial protein synthesisImproves oxygen scavenging-15%内毛虫属内毛虫属等毛等毛纤毛虫纤毛虫属属多毛属多毛属前前毛属毛属改进改进氧气氧气清除清除增加增加微生物微生物蛋白蛋白合成合成以优化瘤胃健康来提高奶牛营养效率达农威益康达农威益康XPXP能优化瘤胃环境能优化瘤胃环境： DiamondVYeastCultureDiamondVYeastCultureOptimizOptimizesesR RumenumenE Environment:nvironment:-StabilizestherumenpH-StabilizestherumenpH 稳定瘤胃酸碱值稳定瘤胃酸碱值-Enhancesoxygenscavenging-Enhancesoxygenscavenging 增加增加瘤胃氧气清除瘤胃氧气清除提高瘤胃效率提高瘤胃效率ImprovesRumenEfficiencyImprovesRumenEfficiency 以优化瘤胃健康来提高奶牛营养效率7.0 6.5 6.0 5.5 5.07.0 6.5 6.0 5.5 5.0微生物产量微生物产量微生物产量微生物产量Microbial YieldMicrobial Yield(g of cells/g of substrate)(g of cells/g of substrate)0.10.10.20.20.30.3pHpH消化淀粉的微生物消化淀粉的微生物Starch digesterStarch digester消化纤维的微生物消化纤维的微生物Fiber digesterFiber digester0.00.0瘤胃酸碱值与细菌族群瘤胃酸碱值与细菌族群Rumen pH and Bacterial Population瘤胃酸碱值瘤胃酸碱值以优化瘤胃健康来提高奶牛营养效率达农威益康达农威益康XP维持较高的瘤胃酸碱值维持较高的瘤胃酸碱值XP Maintained Higher pH5.47a5.81b5.57a5.87bc5.75b6.01c5.05.25.45.65.86.06.20.20.2 g g0.30.3 g g0.40.4 g gControlXPStarch levelpH瘤瘤胃胃酸酸碱碱值值淀粉添加量淀粉添加量Diamond V, 2003对照组益康XP以优化瘤胃健康来提高奶牛营养效率达农威益康达农威益康XPXP能优化瘤胃环境能优化瘤胃环境： DiamondVYeastCultureDiamondVYeastCultureOptimOptimizesizesR RumenumenE Environment:nvironment:-StabilizestherumenpH-StabilizestherumenpH稳定瘤胃酸碱值稳定瘤胃酸碱值- -EnhancesoxygenscavengingEnhancesoxygenscavenging增加增加瘤胃氧气清除瘤胃氧气清除提高瘤胃效率提高瘤胃效率ImprovesRumenEfficiencyImprovesRumenEfficiency以优化瘤胃健康来提高奶牛营养效率瘤胃中的氧气清道夫瘤胃中的氧气清道夫Oxygen Scavengers in The RumenwOxygenscavengingisanimportantaspectofsomerumenbacteriaandOxygenscavengingisanimportantaspectofsomerumenbacteriaandprotozoaprotozoa 氧气的清除氧气的清除，对某些瘤胃细菌与原生虫而言是很重要的对某些瘤胃细菌与原生虫而言是很重要的工作工作wOxygenscavengingruminalfacultativeanaerobicbacteriaOxygenscavengingruminalfacultativeanaerobicbacteria具清除具清除氧气功能之兼性厌氧细菌氧气功能之兼性厌氧细菌StreptococcusbovisStreptococcusbovis 牛链球菌牛链球菌LactobacillusacidophilusLactobacillusacidophilus 嗜酸乳杆菌嗜酸乳杆菌PropionibacteriumacnesPropionibacteriumacnes 痤疮丙酸杆菌痤疮丙酸杆菌wOxygenscavengingOxygenscavengingprotozoaprotozoa具氧气清除功能之原生虫具氧气清除功能之原生虫IsotrichaIsotricha spp.spp.等毛等毛( (纤毛纤毛) )属属DasytrichaDasytrichaspp.spp. 多毛属多毛属 以优化瘤胃健康来提高奶牛营养效率GenusControlControl对照组对照组XPXP益康组益康组Entodinium*EpidiniumDiplodiniumEremoplastromEudiplodiniumOstracodiniumDiploplastromMetadiniumEnoploplastromElytroplastromIsotrichaDasytricha*Unidentified87.72.1-0.21.02.20.81.2-1.10.62.70.469.61.8-0.41.24.32.10.80.20.63.215.50.3肉牛瘤胃中原生虫族群分布百分比肉牛瘤胃中原生虫族群分布百分比PercentgenericdistributionofrumenprotozoainsteersPercentgenericdistributionofrumenprotozoainsteers Arakakietal.,2000.Anim.FeedSci.&Technol.84:121-127533%574%* P 0.05达农威益康达农威益康XP平衡瘤胃原生虫族群平衡瘤胃原生虫族群Balances Rumen Protozoal PopulationImproves oxygen scavenging等毛等毛纤毛虫纤毛虫属属多毛属多毛属改进改进氧气氧气清除清除以优化瘤胃健康来提高奶牛营养效率达农威益康达农威益康XPXP能改善瘤胃与消化道能改善瘤胃与消化道消化率消化率：DiamondVYeastCultureDiamondVYeastCulturei improvesmprovesr ruminaluminala andndt totalotalt tractractd digestion:igestion: 提高瘤胃效率提高瘤胃效率ImprovesFeedEfficiencyImprovesFeedEfficiency以优化瘤胃健康来提高奶牛营养效率57.1*59.3*32.4*35.8*28.5*31.9*37.6*41.1*010203040506070% DigestibilityDMNDFADFHemicelluloseControlXP51.252.953.253.255.355.250515253545556% DigestibilityBermudagrass hayAlfalfa hayControl0.35 g/L XP0.73 g/L XPSullivan and Martin. 1999. J. Dairy Sci. 82:2011-2016.Yoon and Garrett. 1998. World Anim. Prod. Vol 1:322-323.*P 0.05益康益康XPXP提高瘤胃粗饲料消化率提高瘤胃粗饲料消化率XP Increases Ruminal Forage DigestibilityCorn silage digestionAlfalfa and grass hay digestion玉米青贮的消化玉米青贮的消化苜蓿及禾草的消化苜蓿及禾草的消化百慕达干草百慕达干草苜蓿干草苜蓿干草干物质干物质 中洗纤维中洗纤维 酸洗纤维酸洗纤维半纤维半纤维消消化化率率消消化化率率益康XP对照组对照组每升0.35克XP每升0.73克XP以优化瘤胃健康来提高奶牛营养效率61471313746001020304050607080Recovered Kernels, %WholePartial TotalControlXPYoon et al. 1999. J. Anim. Sci. 77(Suppl. 1):82.益康益康XP增加全肠道精料消化率增加全肠道精料消化率XP Increases Concentrate Digestibility未未消消化化玉玉米米的的比比例例整粒玉米整粒玉米部分玉米部分玉米总计总计益康XP对照组以优化瘤胃健康来提高奶牛营养效率达农威益康达农威益康XPXP提高能量和蛋白的供应提高能量和蛋白的供应：DiamondVYeastCultureDiamondVYeastCulturei increasesncreasese energynergya andndp proteinroteins supply:upply:提高生产效率提高生产效率ImprovesProductionEfficiencyImprovesProductionEfficiency以优化瘤胃健康来提高奶牛营养效率212 2122007593137370398426050100150200250300350400450VFA, mM/dAcetatePropionateTotal VFAControlA-MaxXP益康益康XPXP增加能量增加能量( (挥发性脂肪酸挥发性脂肪酸) )的供给的供给XPIncreasesEnergy(VFA)SupplyXPIncreasesEnergy(VFA)SupplyMiller-Webster et al., 2002. J. Dairy Sci. 85:2009-2014+83%P 0.01+15%P 0.04每每日日挥挥发发性性脂脂肪肪酸酸產產量量乙酸乙酸 丙酸丙酸总挥发性脂肪酸总挥发性脂肪酸对照组对照组麦可食麦可食益康益康以优化瘤胃健康来提高奶牛营养效率益康益康XPXP增加瘤胃微生物蛋白至小肠的供给增加瘤胃微生物蛋白至小肠的供给IncreasesMicrobialProteinSupplyIncreasesMicrobialProteinSupplyReference1 微生物蛋白合成微生物蛋白合成 （克（克/天）天）MicrobialProteinMicrobialProteinSynthesis(g/d)Synthesis(g/d)增加量（克增加量（克/天）天）DifferenceDifference(g/d)(g/d)增加百分比增加百分比ImprovementImprovement(%)(%)Hristov et al. (2010) Control XP2081a2275b1949.3AllenandYing(2012)AllenandYing(2012)ControlControlXPXP22632344813.61 1Hristovetal.,2010.Hristovetal.,2010.J.DairySci.93:682-692;AllenandYing,2012.J.DairySci.95:(Inpress)J.DairySci.93:682-692;AllenandYing,2012.J.DairySci.95:(Inpress)a,bP0.1以优化瘤胃健康来提高奶牛营养效率达农威益康达农威益康XPXP酵母培养物的作用机理酵母培养物的作用机理HowDiamondVYeastCultureWorks?HowDiamondVYeastCultureWorks?wStimulates the growth of critical functional rumen microorganisms and optimizes their balance 增加瘤胃重要功能性微生物的增长与平衡增加瘤胃重要功能性微生物的增长与平衡wStabilizes the rumen environment 稳定瘤胃的环境稳定瘤胃的环境Reduces lactate accumulation 降低乳酸在瘤胃的堆积Increases propionate to lactate ratio 提高瘤胃丙酸对乳酸的比例Maintains higher rumen pH 保持较高的瘤胃酸碱值Increases number of oxygen scavenging rumen microorganisms 增加瘤胃内能清除氧气的微生物wImproves ruminal and total tract digestion 增进瘤胃及全肠道消化增进瘤胃及全肠道消化wIncreases energy and protein availability 增加能量及蛋白可利用率增加能量及蛋白可利用率Increases ruminal VFA production (i.e. propionate) 增加瘤胃挥发性脂肪酸的产生（特别是丙酸）Increases microbial protein supply to the small intestine 增加瘤胃微生物蛋白至小肠的供给以优化瘤胃健康来提高奶牛营养效率使用达农威益康使用达农威益康XPXP的应用意义的应用意义PracticalImplicationofUsingDiamondVYeastCulturePracticalImplicationofUsingDiamondVYeastCulture以优化瘤胃健康来提高奶牛营养效率ForageForage粗飼料粗飼料TreatmentTreatment实验组别实验组别AcetateAcetate乙酸乙酸PropionatePropionate丙酸丙酸TotalVFTotalVFA A总挥发性脂肪总挥发性脂肪酸酸Rice strawControl 9.64.014.9稻草稻草XP13.05.319.6Corn stoverControl14.13.718.7玉米秸秆玉米秸秆XP17.35.224.0Corn silage without grainControl13.85.721.1不带棒玉米青贮不带棒玉米青贮XP17.87.827.8Corn silage with grainControl16.46.123.7带棒玉米青贮带棒玉米青贮XP20.78.631.3低质量粗饲料的体外发酵低质量粗饲料的体外发酵Fermentation* of Low Quality Forages* *24hrfermentationandXPat1g/L(24小时发酵，益康XP添加量每升1克)BOLDBOLDindicatessignificantdifferencesatP0.05(加粗字体加粗字体显示统计上有显著差异)Mao et al., 2012以优化瘤胃健康来提高奶牛营养效率中国奶牛的产能表现中国奶牛的产能表现Performance of Dairy Cows in China7%increase7%increase饲料效率提高饲料效率提高7% Zhang et al., 2012以优化瘤胃健康来提高奶牛营养效率中国奶牛的产能表现中国奶牛的产能表现Performance of Dairy Cows in China9%increase9%increase饲料效率提高饲料效率提高9% Zhang et al., 2012以优化瘤胃健康来提高奶牛营养效率奶牛研究总结奶牛研究总结 ResearchSummaryResearchSummary荟萃分析荟萃分析 Meta-analysisMeta-analysisPoppyetal.,2012.J.DairySci.95:(Inpress)以优化瘤胃健康来提高奶牛营养效率奶牛研究总结奶牛研究总结 ResearchSummaryResearchSummary荟萃分析荟萃分析 Meta-analysisMeta-analysisPoppyetal.,2012.J.DairySci.95:(Inpress)以优化瘤胃健康来提高奶牛营养效率奶牛研究总结奶牛研究总结 ResearchSummaryResearchSummary荟萃分析荟萃分析 Meta-analysisMeta-analysisPoppyetal.,2012.J.DairySci.95:(Inpress)以优化瘤胃健康来提高奶牛营养效率益康益康XPXP降低降低瘤胃酸中毒对瘤胃健康及瘤胃酸中毒对瘤胃健康及生产性能的影响生产性能的影响XPReducesNegativeImpactofAcidosisXPReducesNegativeImpactofAcidosisAcidosisproblems瘤胃酸中毒瘤胃酸中毒wlactateproducers生产乳酸的微生物增加wrumenpH瘤胃酸碱值降低wruminalLPS瘤胃脂多糖类增加wfeedefficiency饲料效率降低wmilkfatcontent乳脂率降低wmilkproduction产奶量降低Diamond V solutions 达农威的解决方案达农威的解决方案wlactate utilizers利用乳酸的微生物增加wrumen pH瘤胃酸碱值提高wruminal LPS瘤胃脂多糖类降低wfeed efficiency饲料效率提高wmilk fat content乳脂率增加wmilk production产奶量增加以优化瘤胃健康来提高奶牛营养效率益康益康XPXP维持了较高的乳脂百分比维持了较高的乳脂百分比XPMaintainsHigherMilkFatConcentrationXPMaintainsHigherMilkFatConcentrationLonguski et al., 2009. J. Dairy Sci. 92:160-167正常状况下正常状况下日粮发酵淀粉日粮发酵淀粉挑战挑战乳脂百分比乳脂百分比对照组对照组益康益康XP以优化瘤胃健康来提高奶牛营养效率受日粮含高可发酵碳水化合物的挑战受日粮含高可发酵碳水化合物的挑战 DietaryChallenge:DietaryChallenge:FermentablecarbohydrateFermentablecarbohydrateLonguskietal.,2009.JDairySci.92:160-167.3.5% FCM38404244No challengeChallengeControlXP3.5乳乳脂脂校校正正奶奶量量公斤公斤对照组对照组 益康组益康组非挑战日粮非挑战日粮 挑战日粮挑战日粮 以优化瘤胃健康来提高奶牛营养效率益康益康XPCXPC减少瘤胃内毒素的产生减少瘤胃内毒素的产生ReducesRuminalEndotoxinProductionReducesRuminalEndotoxinProductionLietal.,20Lietal.,2012. .J.DairySci.95(Suppl.1)P = 0.13正常状况下正常状况下瘤胃亚急性酸中毒瘤胃亚急性酸中毒瘤胃脂多醣类浓度瘤胃脂多醣类浓度对照组对照组 益康组益康组以优化瘤胃健康来提高奶牛营养效率益康益康XPXP可可缓和热应激所造成的负面影响缓和热应激所造成的负面影响XPAlleviatesImpactofHeatStressXPAlleviatesImpactofHeatStressHeatstressproblems热应激的影响热应激的影响wrumenmicrobes瘤胃微生物减少wrumenpH瘤胃酸碱值降低wfeedefficiency饲料效率降低wglucosedemand牛只葡萄糖需求增加Diamond V solutions 达农威的解决方案达农威的解决方案wrumen microbes 瘤胃微生物增加wrumen pH 瘤胃酸碱值提高wfeed efficiency 饲料效率提高wruminal propionate 瘤胃丙酸生成增加以优化瘤胃健康来提高奶牛营养效率9HeatStressTrials9HeatStressTrials9 9个热应激试验个热应激试验Milk Production, kg/d环境挑战环境挑战 Environmental Challenge 热应激热应激Heatstress26.627.629.931.428.729.728.530.033.835.036.937.619.622.734.434.939.742.015202530354045Harris & Lobo,1988Harris &Webb, 1990Braun, 1993Nagy et al.,1996NC Farm Trial,1997Fazenda &Soares, 1998Alshaikh et al.,2002Schingoetheet al., 2004Cooke et al.,2007ControlXP对照组对照组益康益康XPXP组组产产奶奶量量 ( (公公斤斤/ /每每天天) )以优化瘤胃健康来提高奶牛营养效率Robinsonetal.,JAS.,1999益康益康XP增加产奶早期牛只的干物质采食量增加产奶早期牛只的干物质采食量XP Increases DMI in Early Lactation产犊前后天数产犊前后天数每每日日干干物物质质采采食食量量的的公公斤斤数数以优化瘤胃健康来提高奶牛营养效率-0.55-0.34-0.50-0.12-0.52-0.39-0.59-0.35-0.29-0.14-0.7-0.6-0.5-0.4-0.3-0.2-0.10.0Body Weight Change, kg/d1 1FirstCalfHeifersirstCalfHeifers1Mature Cows2Mature Cows3Mixed Cows4Mixed CowsControlYeast Culture益康益康XPXP减少牛只在产奶早期的体脂动用减少牛只在产奶早期的体脂动用 XPReducesTissueMobilizationPost-calvingXPReducesTissueMobilizationPost-calving1RobinsonandGarrett.1999.JAS.77:988-999;2Dannetal.,2000.JDS.83:123-127;3Erasmusetal.,2005.AFST.122:219-239;4Robinson.1997.JDS.80:1119-1125平均每日减少下降平均每日减少下降 0.22公斤公斤Averagedailysavingof0.22kg/dAveragedailysavingof0.22kg/d头胎牛头胎牛 经产牛经产牛 经产牛经产牛 头胎牛头胎牛+ +经产牛经产牛 头胎牛头胎牛+ +经产牛经产牛每每日日体体重重改改变变公公斤斤数数对照组对照组益康益康XPXP组组以优化瘤胃健康来提高奶牛营养效率益康益康XPXP增加奶牛日粮能量浓度增加奶牛日粮能量浓度 XPXPIncreasesEnergyDensityofDairyRationsIncreasesEnergyDensityofDairyRationsItemParity 胎次胎次Control 对照对照Diamond V 益康益康Robinson, 1997 Robinson and Garrett, 1999Dann et al., 2000Erasmusetal.,2005Erasmusetal.,2005MultiparousPrimiparousMultiparousMixed parityMultiparous1.841.641.721.361.531.901.651.821.491.68Average平均平均日粮能量浓度日粮能量浓度Difference (Mcal/kgDM)每公斤日粮干物质增加能量每公斤日粮干物质增加能量Difference(Mcal/d23kgDMI)2323公斤日粮干物质增公斤日粮干物质增加能量加能量1.621.710.092.07*Improved energy density of diets in early lactation cows (5.5%)!产奶早期日粮能量浓度增加产奶早期日粮能量浓度增加5.5兆卡兆卡兆卡兆卡头胎牛头胎牛+ +经产牛经产牛 头胎牛头胎牛 经产牛经产牛 经产牛经产牛 经产牛经产牛 兆卡兆卡以优化瘤胃健康来提高奶牛营养效率Schingoethe et al., 2004. J. Dairy Sci. 87:4178-4181益康益康XP提高饲料效率提高饲料效率XP Improves Feed Efficiency南达科他州立大学研究,益康增加饲料效率8%South Dakota State University 8% improvement with XPItemControlControl对照组对照组XPXP益康益康DMI,kg/dDMI,kg/d 干物质采食量干物质采食量23.122.1Milk,kg/dMilk,kg/d 产奶量产奶量34.935.44%FCM,kg/d4%FCM,kg/d4%4%乳脂校正奶乳脂校正奶31.232.0Feedefficiencyefficiency 饲料效率饲料效率1.38a1.49ba,b P 0.05以优化瘤胃健康来提高奶牛营养效率ResearchSourcesResearchSources研究来源研究来源ControlControl对照组对照组XPXP益康益康Hippen et al., 20101.561.66Allen et al., 20071.481.55Cooke et al., 20071.511.64Schingoethe et al., 20041.471.58Alshaikh et al., 20020.801.07Average(+10%)Average(+10%) 平均平均(增加增加10%)1.361.50饲料效率饲料效率 = 3.5%乳脂校正乳乳脂校正乳干物质采食量干物质采食量 Feed Efficiency = 3.5% FCM/DMI益康益康XPXP提高提高产奶中期牛只饲料效率产奶中期牛只饲料效率FeedEfficiencyinMid-lactationCowsFeedEfficiencyinMid-lactationCows以优化瘤胃健康来提高奶牛营养效率以益康来管理风险与最大化产奶潜能以益康来管理风险与最大化产奶潜能ManageRiskManageRisks sandMaximizeProductionEfficiencywithandMaximizeProductionEfficiencywithXPXP Better Resist to Ration VariationReduceImpactofReduceImpactofRumenRumenAcidosisMinimize NegativeEnergy BalanceMaximizeMaximizeF Feed EfficiencyGreater Use ofLow Quality ForageRumen EfficiencySave Cost onHigh Priced FeedAlleviate Impact ofHeat StressOptimize Rumen Fermentation降低瘤胃过酸的降低瘤胃过酸的负面影响负面影响增加使用低质量增加使用低质量粗饲料粗饲料减少使用高价格减少使用高价格饲料来降低成本饲料来降低成本饲料效率饲料效率最大化最大化负能量平衡负能量平衡最小化最小化减轻热应激带来减轻热应激带来的负面影响的负面影响对日粮变异有对日粮变异有更佳的抵抗力更佳的抵抗力瘤胃功能优化瘤胃功能优化以优化瘤胃健康来提高奶牛营养效率总结总结 SummarySummarywSub-optimalrumenfunctionlimitsproductionpotentialofdairycattle.次优化的瘤胃功能限制了牛只产奶潜次优化的瘤胃功能限制了牛只产奶潜能能wDietarymodificationwithscientificallyprovenfeedsupplementsuchasDiamondVYeastCulturecanhelpimprovetherumenhealthandproductivityofdairycattleandmaximizetheprofitability.以经科研证实的饲料添加以经科研证实的饲料添加剂剂，如达农威如达农威益康益康XP酵母培养物酵母培养物，来改善日来改善日粮质量粮质量，可以帮助改善瘤胃功能、提高奶牛可以帮助改善瘤胃功能、提高奶牛产能、与加大产能、与加大產業產業盈利能力盈利能力以优化瘤胃健康来提高奶牛营养效率不推荐活酵母的原因不推荐活酵母的原因 WhyNotLiveYeast?WhyNotLiveYeast?因为活酵母因为活酵母 Because live yeast w在储存期间不能维持活性在储存期间不能维持活性 Isunabletomaintainviabilityduringstoragew对热处理敏感对热处理敏感( (例如制粒例如制粒) )Issensitivetoheattreatment(i.e.pelleting)w在预混料中丧失活性迅速在预混料中丧失活性迅速 Loseviabilityfastinpremixesw在瘤胃中丧失活性迅速在瘤胃中丧失活性迅速 Loseviabilityquicklyintherumen 产品稳定性差异大产品稳定性差异大无法无法预期一致性的产品效益预期一致性的产品效益！ Variableproductstability.Variableproductstability.cancant texpectconsistentproductbenefits!expectconsistentproductbenefits!以优化瘤胃健康来提高奶牛营养效率77%loss77%loss 损失损失维持活性干酵母菌的活性维持活性干酵母菌的活性MaintainingADYViabilityMaintainingADYViability 高温高温 （35C） 室温室温 （21C） 冷藏冷藏 （7C）周数周数Diamond V以优化瘤胃健康来提高奶牛营养效率制粒会杀死活性干酵母制粒会杀死活性干酵母PelletingKillsADYPelletingKillsADYEffectofpelletingonyeastviabilityinfeedsffectofpelletingonyeastviabilityinfeeds 制粒对日粮中活性干酵母的影响制粒对日粮中活性干酵母的影响Yeast Viability (cfu/g)TestBeforePelletingAfterPelletingLossA7.8 x1048.7 x10199.9%B8.6 x1043.6 x10395.8%C3.4 x1056.7 x10299.8%D9.0 x1051.2 x10586.7%E1.1 x1063.8 x10496.5%F5.3 x1065.1 x10590.4%Conducted by Diamond V Mills酵母菌活性酵母菌活性制粒前制粒前制粒后制粒后活性损失活性损失以优化瘤胃健康来提高奶牛营养效率达农威益康达农威益康XPXP酵母代谢产物功能不受制粒影响酵母代谢产物功能不受制粒影响 PelletingdoesnotaffectDiamondVNutritionalPelletingdoesnotaffectDiamondVNutritionalMetabolitesMetabolites VFA concentration, mM22.9a27.9b28.0b24.8a28.3b28.4b51.4a61.2b61.8b010203040506070AcetatePropionateTotalControlPelleted XPXP乙酸乙酸 丙酸丙酸总计总计挥挥发发性性脂脂肪肪酸酸浓浓度度mMmM对照组对照组XP制粒制粒XP未制粒未制粒Diamond V, 2003以优化瘤胃健康来提高奶牛营养效率-69%-95%美国堪萨斯州美国堪萨斯州州州立大学立大学Bradford教教授授对活性干酵母菌的活性研究对活性干酵母菌的活性研究目标：目标：8.34刚混合后刚混合后混合两周后混合两周后每每克克含含有有菌菌落落生生成成单单位位与粉碎玉米与粉碎玉米混合混合与维他命与与维他命与矿物质盐混矿物质盐混合合以优化瘤胃健康来提高奶牛营养效率酵母菌在奶牛瘤胃中的活力酵母菌在奶牛瘤胃中的活力 YeastViabilityintheRumenofLactatingDairyYeastViabilityintheRumenofLactatingDairyCowsCowsBruns et al., 2011-57%-86%-96%-98%-70%饲喂酵母菌后小时数饲喂酵母菌后小时数酵酵母母菌菌数数每每克克可可形形成成菌菌落落数数以优化瘤胃健康来提高奶牛营养效率结论结论 ConclusionConclusionw地球人口预计在地球人口预计在20502050年时超过年时超过9090亿人亿人, ,对农产品的需求持续增对农产品的需求持续增加中加中 Human population is estimated to be exceed 9 billion by the year 2050 and demand for agricultural products is increasing.w对饲料原料的高度需求对饲料原料的高度需求, ,造成乳产品生产成本提高造成乳产品生产成本提高 Increasing demand for feed resources push the cost of dairy production higher.w對對饲料的有效利用饲料的有效利用, ,可达到更具经济效益的乳产品生产可达到更具经济效益的乳产品生产 Efficient use of feeds can help achieve more cost effective dairy production. w经科学研究证实经科学研究证实，达农威达农威益康益康XP酵母培养物是改善饲料效率酵母培养物是改善饲料效率与提高奶业盈利能力的一个有效工具与提高奶业盈利能力的一个有效工具 Scientific evidences proved that Diamond V Yeast Culture can be an effective tool to improve feed efficiency and to maximize the profitability of dairy operations.以优化瘤胃健康来提高奶牛营养效率謝謝謝謝!ThankYouThankYou! !Whatquestionsdoyouhave?Whatquestionsdoyouhave?问题问题? ?以优化瘤胃健康来提高奶牛营养效率以优化瘤胃健康来提高奶牛营养效率