干细胞研究及其临床应用干细胞研究及其临床应用组织胚胎学教研室组织胚胎学教研室 李秋明李秋明Your company sloganYour company sloganLOGOLOGOLOGOLOGO 1 Introduction1 Introduction 2 2 AApplicationpplication 3 Challengers Forward3 Challengers Forward 4 Conclusion4 ConclusionYour company sloganYour company sloganLOGOLOGOLOGOLOGOIntroduction胚胎干细胞胚胎干细胞（embryonic stem cells, embryonic stem cells, ESCsESCs）成体干细胞成体干细胞（adult/tissue-specific stem cells, adult/tissue-specific stem cells, ASCsASCs）Your company sloganYour company sloganLOGOLOGOLOGOLOGO成体干细胞成体干细胞（adult/tissue-specific stem cells, adult/tissue-specific stem cells, ASCsASCs）胰腺、肝、角膜、骨髓、脂肪、脑、胰腺、肝、角膜、骨髓、脂肪、脑、胰腺、肝、角膜、骨髓、脂肪、脑、胰腺、肝、角膜、骨髓、脂肪、脑、肌组织、肺、皮肤等处干细胞肌组织、肺、皮肤等处干细胞肌组织、肺、皮肤等处干细胞肌组织、肺、皮肤等处干细胞肿瘤干细胞（肿瘤干细胞（肿瘤干细胞（肿瘤干细胞（tumor stem cell, tumor stem cell, TSCsTSCs）Your company sloganYour company sloganLOGOLOGOLOGOLOGOYour company sloganYour company sloganLOGOLOGOLOGOLOGOYour company sloganYour company sloganLOGOLOGOLOGOLOGOYour company sloganYour company sloganLOGOLOGOLOGOLOGOYour company sloganYour company sloganLOGOLOGOLOGOLOGOYour company sloganYour company sloganLOGOLOGOLOGOLOGOYour company sloganYour company sloganLOGOLOGOLOGOLOGOYour company sloganYour company sloganLOGOLOGOLOGOLOGOApplication临床应用临床应用( ( ( (细胞、组织、细胞、组织、细胞、组织、细胞、组织、器官替代器官替代器官替代器官替代) ) ) )退行性疾病退行性疾病损伤再生损伤再生免疫性疾病免疫性疾病肿瘤肿瘤其他其他Your company sloganYour company sloganLOGOLOGOLOGOLOGO人类发育模型人类发育模型人类发育模型人类发育模型基因操作基因操作基因操作基因操作药物筛选药物筛选药物筛选药物筛选基础研究基础研究Your company sloganYour company sloganLOGOLOGOLOGOLOGO定向诱导定向诱导定向诱导定向诱导分化机制分化机制分化机制分化机制不明确不明确不明确不明确分离、扩增及分离、扩增及分离、扩增及分离、扩增及鉴定成体干细鉴定成体干细鉴定成体干细鉴定成体干细胞胞胞胞排斥反应、排斥反应、排斥反应、排斥反应、伦理等伦理等伦理等伦理等体外长期培体外长期培体外长期培体外长期培养的安全性养的安全性养的安全性养的安全性Challengers ForwardYour company sloganYour company sloganLOGOLOGOLOGOLOGO具空间构具空间构具空间构具空间构型及正常型及正常型及正常型及正常生理功能生理功能生理功能生理功能的克隆器的克隆器的克隆器的克隆器官移植官移植官移植官移植定向诱导定向诱导定向诱导定向诱导或或或或/ / / /及基因及基因及基因及基因修饰，经修饰，经修饰，经修饰，经筛选后将筛选后将筛选后将筛选后将所需细胞所需细胞所需细胞所需细胞移植移植移植移植针对组织针对组织针对组织针对组织类型，直类型，直类型，直类型，直接移植相接移植相接移植相接移植相应的成体应的成体应的成体应的成体干细胞干细胞干细胞干细胞ConclusionYour company sloganYour company sloganLOGOLOGOLOGOLOGO