ECMO OXYGENATORSSilicone Rubber Sheet Membranes Medtronic/AvecorRange of 5 sizes 0.8 - 4.5 M2FDA Approved for long term useMicroporous Hollow Fiber DevicesLimited duration of use do to plasma leak Medtronic Minimax - Polypropylene hollow fibers Infant/PediatricPlasma resistant fibers (PRF)Carmeda Coated (Heparin Bioactive surface)Medtronic Affinity - Polypropylene hollow fibers Large Peds and AdultsJostra Quadrox DPolymethylpentene fibersNo Plasma leakMICRO POROUS POLYPROPYLENE HOLLOW FIBERSMICRO POROUS POLYPROPYLENE HOLLOW FIBERSQUADROXOxygenation SystemQuadrox De-airingde-airingblood inQuadrox Rear viewgas ingas outwater inwater outluer portrecirculationblood outsampling porttemperature probeBlood FlowDe-airing membranepre chamberblood inblood outLuer portBlood Flowchamber Achamber BGas Distributionchamber Achamber BDistribution of Water Flowchamber Achamber BMembrane Structure7000 nmMicroporous membranepore size max. 0.2 mbloodpathgaspath0,12 nmPolypropylene Membrane StructureQuadrox Diffusion MembraneTechnical DataQuadroxQuadrox DBlood flow rate0.5 7 l/min0.5 7 l/minPriming volume250 ml250 mlOxygenation membrane1.8 mpolypropylene1.8 mpolymethylpenteneMax. O2-transfer425 ml/min425 ml/minMax. CO2-transfer320 ml/min320 ml/minHeat exchanger0.6 m polyurethane0.6 m polyurethaneBlood Flow DirectionBottom-to-BottomBottom-to-BottomMax. water pressure14 psi (1bar)14 psi (1bar)Gas Exchange in the Artificial LungDiffusion controlled fixed variablesSurface area, membrane material, blood path thickness (boundary layer)Gradient drivenFio2 for O2 TransferNet Gas flow for CO2 TransferMembrane Structure7000 nmMicroporous membranepore size max. 0.2 mbloodpathgaspath0,12 nm